Essential Biochemistry, 5th Edition

Essential Biochemistry, 5th Edition

By Charlotte Pratt and Kathleen Cornely

$76.95  USD | $98.95  CAN

Essential Biochemistry 5th Edition combines succinct and clear chapters with extensive problem sets in a new WileyPLUS experience that features even more video tutorials and interactive questions. Students benefit from a modern approach involving broad, but not overwhelming coverage of biochemical facts, focusing on the chemistry behind biology. Because effective learning also requires students to become as fully engaged with the material as possible, the authors employ a strategy of posing questions and suggesting study activities throughout each chapter, providing students with practical knowledge and problem-solving opportunities throughout. Interactive guided tours throughout WileyPLUS ensure that students will not simply read and memorize, but will explore and discover on their own and view a truer picture of how biochemists approach their work in the laboratory or clinic.

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Hear from our Authors

Guided Tours

Created by Charlotte Pratt, these multipart animations present “big picture” concepts through animations, tutorials, and practice to help students truly understand concepts that may be difficult to grasp. Three new Guided tours have been added to new WileyPLUS for the 5th Edition:

  • Water and pH
  • Motor proteins
  • Glycolysis and the citric acid cycle

Sample Calculation Videos

Students come to biochemistry with different levels of math skills. These videos, created by Charlotte Pratt, walk students through the Sample Calculations provided for key equations throughout the course.

Bioinformatics Exercises:

Written by Rakesh Mogul, Cal Poly Pomona, these brief assignable brief exercises introduce students to the rich variety of biochemical information and software tools available on the internet, showing them how to mine this information and illuminating the connection between theory and applied concepts.

What’s New

  • Essential Biochemistry 5th Edition includes a new WileyPLUS course that provides an enhanced and immersive learning experience. Instructors can customize their courses by taking advantage of a more flexible course design and improved assessment capabilities. Students now have access to recommended assignments, varied learning tools, and a more personalized experience.
  • Fully revised and updated material throughout, based on the latest scientific discoveries and advances in biochemistry.
  • A major new section in Chapter 5 on immunoglobulins that covers antibody structure, modular construction of other immune system proteins, and techniques based on antibodies.
  • Additional chemistry topics that provide deeper explanations of reaction mechanisms, a complete Calvin cycle diagram, and new topics such as microbial redox pathways and polyamines
  • More real-life applications, such as drugs, food chemistry, and lab techniques throughout the 5th edition.
  • Three new Guided Tours in WileyPLUS. Including interactive questions at the end of each tour, these author-prepared video tutorials cover:

    – Water and pH
    – Motor proteins
    – Glycolysis and the citric acid cycle

CHARLOTTE PRATT received a B.S. in biology from the University of Notre Dame and a Ph.D. in biochemistry from Duke University. She is a protein chemist who has conducted research in blood coagulation and inflammation at the University of North Carolina at Chapel Hill. She is currently Associate Professor in the Biology Department at Seattle Pacific University. Her interests include molecular evolution, enzyme action, and the relationship between metabolic processes and disease. She has written numerous research and review articles, has worked as a textbook editor, and is a co-author with Donald Voet and Judith G. Voet of Fundamentals of Biochemistry, published by John Wiley & Sons, Inc.


KATHLEEN CORNELY holds a B.S. in chemistry from Bowling Green (Ohio) State University, an M.S. in biochemistry from Indiana University, and a Ph.D. in nutritional biochemistry from Cornell University. Her experimental research has included a wide range of studies of protein purification and chemical modification. She currently serves as a Professor of Chemistry and Biochemistry at Providence College where she has taught courses in biochemistry, organic chemistry, and general chemistry. Her recent research efforts have focused on chemical education, particularly the use of case studies and guided inquiry in biochemistry education. She serves on the editorial board of Biochemistry and Molecular Biology Education and is a member of the American Society for Biochemistry and Molecular Biology.

PART 1: Foundations
Chapter 1: The Chemical Basis of Life
Chapter 2: Aqueous Chemistry

Chapter 3: From Genes to Proteins
Chapter 4: Protein Structure
Chapter 5: Protein Function
Chapter 6: How Enzymes Work
Chapter 7: Enzyme Kinetics and Inhibition
Chapter 8: Lipids and Membranes
Chapter 9: Membrane Transport
Chapter 10: Signaling
Chapter 11: Carbohydrates

Chapter 12: Metabolism and Bioenergetics
Chapter 13: Glucose Metabolism
Chapter 14: The Citric Acid Cycle
Chapter 15: Oxidative Phosphorylation
Chapter 16: Photosynthesis
Chapter 17: Lipid Metabolism
Chapter 18: Nitrogen Metabolism
Chapter 19: Regulation of Mammalian Fuel Metabolism

Chapter 20: DNA Replication and Repair
Chapter 21: Transcription and RNA
Chapter 22: Protein Synthesis

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